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Date:2019-09-30
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弱视是种由于幼年时期眼球斜视或屈光参差，导致眼-脑协调异常引发的病变，是我国青少年单眼视力障碍最主要因素。患者在没有得到及时有效治疗情况下，可能引起永久性单眼视力损伤甚至失明。然而，目前对于弱视的治疗多集中在其“眼”的部分，神经机制远远未明。我们前期成果显示，弱视人群脑功能异常并不仅限于低级视觉皮层，尚包含丘脑，纹状体皮层及顶叶，颞叶等负责高级视觉功能的皮层区域。因此，本项目拟通过无创的多模态神经成像技术，针对儿童弱视治疗前后脑可塑性变化来阐明这一科学问题，并从神经层面客观、量化、系统地评估治疗。
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