Lulu Cai
+
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Personal Information
Gender:Female
E-Mail:
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Gender:Female
E-Mail:3f576bce2f9b26ea560371e96fc27ce0ca4797c1cd74fe3d9d9fa48ab04aed191dcc2bdecaf1a8cde9fa1a59caa7ef194a303b906cd21df70b7d839ff1c9640a5f3dbd0e6761f2b020bdd6c46d471e80a9f2073860ca00fad2f4937d00e6d6fb24b7dee4e4dc9438e6bd1b669d93f82c4b6d9858020b214a72c83429440af8df
Affiliation of Author(s):[1]四川省医学科学院·四川省人民医院药学部,四川成都610072;[2]电子科技大学医学院个体化药物治疗四川省重点实验室,四川成都610072
Journal:Chinese Journal of New Drugs and Clinical Remedies
Key Words:tumor microenvironment;macrophages;molecular targeted therapy;signaling pathways
Abstract:The tumor microenvironment refers to the non-cancerous cells and components in the tumor,which plays an important role in promoting the occurrence,development,metastasis and the response to treatment of tumors.Among them,the tumor immune microenvironment(TIME)composed of immune cells and extracellular matrix has attracted much attention.These immunosuppressive components build the tumor immune barrier and promote the immune escape of tumor cells.Therefore,TIME can be used as a therapeutic target for cancer.The characteristics of TIME and the latest progress of the current targeted therapy strategy were summarized in this article,providing ideas for targeted therapy based on TIME.
Volume:43
Issue:2
Page Number:120-127
ISSN No.:1007-7669
Translation or Not:no
CN No.:31-1746/R
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