Lulu Cai
+
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Personal Information
Gender:Female
E-Mail:
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Gender:Female
E-Mail:3f576bce2f9b26ea560371e96fc27ce0ca4797c1cd74fe3d9d9fa48ab04aed191dcc2bdecaf1a8cde9fa1a59caa7ef194a303b906cd21df70b7d839ff1c9640a5f3dbd0e6761f2b020bdd6c46d471e80a9f2073860ca00fad2f4937d00e6d6fb24b7dee4e4dc9438e6bd1b669d93f82c4b6d9858020b214a72c83429440af8df
Affiliation of Author(s):[1]Department of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan...
Journal:Journal of Controlled Release
Key Words:Hernia mesh; Anti-fibrosis; Photoacoustic imaging; TGF-beta signaling; Drug delivery
Abstract:Postoperative recurrence after incisional hernia repair remains a significant clinical challenge, with mesh contraction from the fibrotic foreign body response as an important contributing factor. Meanwhile, the inherent radiolucency of standard polypropylene (PP) meshes hinders postoperative imaging assessment. To address this, we developed a versatile mesh, SB431542@MPDA-PP, by functionalizing a medical-grade PP mesh with mesoporous polydopamine (MPDA) nanoparticles for localized drug delivery and intrinsic photoacoustic (PA) imaging. The mesh achieved high encapsulation loading (97.13%)...
Volume:394
Page Number:114897
ISSN No.:0168-3659
Translation or Not:no
Address: Shahe Campus:No.4, Section 2, North Jianshe Road, 610054 | Qingshuihe Campus:No.2006, Xiyuan Ave, West Hi-Tech Zone, 611731 | Chengdu, Sichuan, P.R.China © 2010 University of Electronic Science and Technology of China. All Rights Reserved
Click: | The Last Update Time:.. | University of Electronic Science and Technology of China