I. Basic Information:
Name: Wang Yi
Graduated from: Sichuan University
Degree: Doctor of Science
Current employer: Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital
University of Electronic Science and Technology of China Medical School master tutor
Doctoral supervisor of Biomedical Engineering, University of Electronic Science and Technology of China
Title: Researcher
Ⅱ. Educational Background
July 2012-June 2014 Postdoctoral Fellow at Ohio State University/All American Children's Hospital, USA
Sept. 2009-Jun. 2012 Doctor of Science, School of Life Science, Sichuan University
Sep. 2003 -- Jul. 2007 Master of Science, School of Life Science and Biopharmaceutical, Shenyang Pharmaceutical University
Sept. 1998-Jul. 2002 Bachelor of Engineering, Department of Chinese Medicine, Shenyang Pharmaceutical University
Ⅲ. Awards and Honors
Third Prize of Sichuan Science and Technology Award, 2022
First Prize of Sichuan Medical Science and Technology Progress Award, 2021
The 14th batch of academic and technical leaders of Sichuan Provincial Health and Family Planning Commission, August 2020
Tianfu Ten Thousand People Plan · Tianfu Science and Technology Elite, 2019
Sichuan Medical Association Youth Outstanding Paper Award, 2019
3rd Global Congress on Obesity and Diet Management, Amsterdam, Netherlands, Outstanding Paper Award, 2018
The 12th batch of candidates for academic and technical leaders in Sichuan Province, 2018
Health Guardian for the New Era, 2018
Excellent Paper Award of Sichuan Hospital Association, 2018
2018-2019 Xenotransplantation Magazine the most downloaded paper certificate
Sichuan Medical Science and Technology Award, First Prize, 2017
Identity certificate for overseas students of Sichuan Province
Identity certificate of high-level overseas students
Licensed pharmacist qualification certificate
Professional and technical position Qualification Certificate (Associate Researcher Qualification Certificate)
The 12th batch of candidates for academic and technical leaders of Sichuan Health and Family Planning Commission, 2016
Global Congress on Stem Cells and Cell Science, Barcelona, Spain, Excellent Paper Award, 2016
Excellent scientific research paper of Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, third prize, 2014
Sichuan University second-class Scholarship, 2009-2012
Excellent Scientific Research Secretary of Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, 2011
Excellent Scientific Research Secretary of Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, 2010
Excellent scientific research Paper of Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, first prize, 2010
Excellent Scientific Research Secretary of Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, 2009
In 2009, GCP certificate of drug Clinical research
Ⅳ. Scientific Research Experience
I am mainly engaged in research on islet transplantation, islet regeneration, cell cycle signal transduction, tumor and related signaling mechanisms. I have carried out pharmacology related research and new drug research and development for more than ten years, focusing on major diseases that endanger people's health, such as cancer, diabetes and its complications. I have published more than 70 papers in total, among which I have published more than 40 SCI papers as the first author (including co-first author) and corresponding author (including co-corresponding author). Invited to 2021 International Xenotransplantation Conference, 2020 International Transplantation Congress in Seoul, Korea, Cell Symposium in San Francisco, USA: He also delivered speeches at Gene and Cell Therapy 2020, the International Transplantation Congress in Munich, Germany, the World Cancer Action Congress and Stem Cell and Cell Science Congress in Spain, and the Third Global Congress on Obesity and Diet Management in Amsterdam, the Netherlands. He has presided over and participated in more than 20 national, provincial and ministerial level and bureau level projects, including National Natural Science Foundation, Sichuan Provincial Science and Technology Department Fund, Sichuan Provincial Human Resources and Social Security Department Fund, Sichuan Provincial Health and Family Planning Commission Fund, Chengdu Municipal Science and Technology Bureau Fund, Sichuan Medical Association Fund, etc. Honorary titles include Tianfu Ten Thousand Plan · Tianfu Science and Technology Elite, Backup candidate for Academic and Technology Leader of Sichuan Province, Academic and Technology Leader of Sichuan Provincial Health and Family Planning Commission, high-level Overseas Students of Sichuan Province, Health Guardian of the New Era, and my research achievements won the first prize of Sichuan Medical Science and Technology Award.
Ⅴ. Publish the following articles as the first or corresponding author:
Chunming Cheng, Si Zhang, Donglin Guan, Yi Wang, Nidhi Jyotsana. Editorial: Tumor metabolism: From molecular mechanisms to clinical application. Frontiers in Cell and Development Biology. 2023. (corresponding author)
Hong Liang, Xia He, Yitong Tong, Niuniu Bai, Yushu Pu, Ke Han, Yi Wang. Ferroptosis open a new door for colorectal cancer treatment. Frontiers in Genetics. 2023 (corresponding author)
Xueliang Yi, Xuemei Tang, Tianlong Li, Lin Chen, Hongli He, Xiaoxiao Wu, Chunlin Xiang, Min Cao, Zixiang Wang, Yi Wang, Yiping Wang, Xiaobo Huang. Therapeutic potential of the sphingosine kinase 1 inhibitor, PF-543. Biomedicine & Pharmacotherapy (corresponding author)
Ling Xua, Yu’e Liu, Xi Chen, Hua Zhong, Yi Wang. Ferroptosis in life: To be or not to be. Biomedicine & Pharmacotherapy. 2023, 159,114241.(corresponding author)
Yu’e Liu, Yihong Sun, Yadong Guo, Xiaoyun Shi, Xi Chen, Wenfeng Feng, Lei-Lei Wu, Jin Zhang, Shibo Yu, Yi Wang, Yufeng Shi. An Overview: The Diversified Role of Mitochondria in Cancer Metabolism. International Journal of Biological Science. 2023, 19, 897-915.(corresponding author)
Bo Gong, Yi Liang, Qian Zhang, Huan Li, Jialing Xiao, Liang Wang, Han Chen, Wenjie Yang, Xiaoqing Wang, Yi Wang, Zongze He. Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma. Journal of Genetics and Genomics. 2023 Jan 25;S1673-8527(23)00023-1. (corresponding author)
Qiao Zhou, Li Long, Xixi Chen, Xiaobo Huang, Shaoping Deng, Yi Wang. Identification of methylated differentially expressed hub genes in systemic lupus erythematosus patients by WGCNA based epigenome-wide and transcriptome-wide analysis. Genes & Diseases. (corresponding author)
Fei Xiong, Qiao Zhou, Xiaobo Huang, Peng Cao, Yi Wang. Ferroptosis plays a novel role in nonalcoholic steatohepatitis pathogenesis. Frontiers in Pharmacology. 2022, December 2, 13, 1055739 (corresponding author)
Tiantian Lei, Lin Chen, Kejing Wang, Suya Du, Carmen Gonelle-Gispert, Yi Wang, Leo H. Buhler. Genetic engineering of pigs for xenotransplantation to overcome immune rejection and physiological incompatibilities: The first clinical steps. Frontiers in Immunology.2022, December 6, 10, 1031185 (corresponding author)
Zhen Geng, Qi Zhang, Ting Li, Ting Huang, Hailian Wang, Qiao Zhou, Shaoping Deng, Yanshuang Zhao, Yanjiao Li, Chunming Cheng, Carmen Gonelle-Gispert, Leo H. Buhler and Yi Wang. Advantages of the retroperitoneal retrocolic space as the transplant site for encapsulated xenogeneic islets. Xenotransplantation. 2022 Dec 1;e12787. (corresponding author)
Meng Zhang, Qian Lei, Xiaobo Huang, Yi Wang. Molecular mechanisms of ferroptosis and the potential therapeutic targets of ferroptosis signaling pathways for glioblastoma. Front. Pharmacol. 2022;13:1071897 (corresponding author)
Xia He, Ning Wang, Yu Zhang, Xiaobo Huang, Yi Wang. The therapeutic potential of natural products for treating pancreatic cancer. Front. Pharmacol, 2022;13:1051952 (corresponding author)
Fan Zeng, Yunping Lan, Ning Wang, Lijing Yang, Xiaobo Huang, Qiao Zhou, Yi Wang. Ferroptosis, a new therapeutic target for bladder cancer. Front. Pharmacol. 2022;13:1043283(corresponding author)
Qiao Zhou, Ting Li, Qin Qin, Ning Wang, Xiaobo Huang and Yi Wang. The Relationship between ferroptosis and lymphoma: emerging mechanisms and a novel therapeutic approach. Front. Genetics. 2022;13: 1039951 (corresponding author)
Qiao Zhou, Ting Li, Kaiwen Wang, Qi Zhang, Zhuowen Geng, Shaoping Deng, Chunming Cheng and Yi Wang. Current Status of Xenotransplantation Research and the Strategies for Preventing Xenograft Rejection. Front. Immunol. 2022;13:928173. (corresponding author)
Li Long, Hongmei Guo, Xixi Chen, Yan Liu, Ruyi Wang, Xiaomei Zheng, Xiaobo Huang, Qiao Zhou, Yi Wang. Advancement in understanding the role of ferroptosis in Rheumatoid arthritis. Front. Physiol., 04 October 2022;13:1036515. (corresponding author)
Lu Yu, Minghan Sun, Qi Zhang, Qiao Zhou, Yi Wang. Harnessing the immune system by targeting immune checkpoints: providing new hope for oncotherapy. Front. Immunol. 2022;13:982026. (corresponding author)
Guanghui Du, Qi Zhang, Xiaobo Huang,Yi Wang, Molecular mechanisms of ferroptosis and its role in the occurrence and treatment of diabetes. Frontiers in Genetics, 2022;13:1018829. (corresponding author)
Qiao Zhou, Lijing Yang, Ting Li, Kaiwen Wang, Xiaobo Huang, Jingfen Shi and Yi Wang. Mechanisms and inhibitors of ferroptosis in psoriasis. Frontiers in Molecular Biosciences.2022;9:1019447. (corresponding author)
Yi Wang, Yuya Wang, Yifei Ren, Qi Zhang, Ping Yi, Chunming Cheng. Metabolic modulation of immune checkpoints and novel therapeutic strategies in cancer. Semin Cancer Biol. 2022 Feb 10; S1044-579X(22)00031-1.
Qiao Zhou, Qi Zhang, Kevin Wang, Ting Huang, Shaoping Deng, Yi Wang, Chunming Cheng. Anti-rheumatic drug-induced hepatitis B virus reactivation and preventive strategies for hepatocellular carcinoma. Pharmacol Res. 2022 Mar 15;178:106181.(corresponding author)
Qi Zhang, Yanjiao Li, Zhen Geng, Sandrine Gerber, Yi Wang, Leo H. Bühler. Islet encapsulation: new developments for the treatment of type 1 diabetes. Front. Immunol. 2022;13:869984. (corresponding author)
Suya Du, Yanjiao Li, Zhen Geng, Qi Zhang, Leo H. Buhler, Carmen Gonelle-Gispert and Yi Wang. Engineering Islets from Stem Cells: the optimal solution for the treatment of diabetes? Front. Immunol. 2022;13:869514. (corresponding author)
Mi Zhou, Da Xu, Wenjun Zhang, Yi Wang, Mingliang Zuo, Siming Wang, Ting Liu, Junqing Zhang, Lixue Yin, Zhiyu Guo, Jun Liu, Jing Tan. The hepato-cardiac disorders in Tibetan residents with hepatic echinococcosis: A case–control echocardiography study. Journal of Clinical Ultrasound. 2022;50(9):1251-1259.
Yi Wang, Xie Q, Tan H, Liao M, Zhu S, Zheng LL, Huang H, Liu B. Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies. Pharmacol Res. 2021;173:105702.
Ji-Chao Tang, Wang-Jie Suolang, Chong Yang, Yi Wang, Ming-Wu Tian, Yu Zhang. Monosegmental ALPPS combined with ante-situm liver resection: A novel strategy for end-stage hepatic alveolar echinococcosis. Hepatobiliary Pancreat Dis Int. 2021;21(2):186-189.
Zhang Yu, Xie Ping, Yang Chong,Wang Yi, Liu Xingchao, Yang Hongji, Liu Jun, Zhou Guo, Deng Shaoping. The Value of Hepatic vein Stent Placement as a Bridge Therapy on Treating Hepatic Alveolar Echinococcosis Presenting with Budd-Chiari Syndrome. Annals of surgery. 2021;273(4):e154-e156.
Suping Li, Jing Fu, Yi Wang, Chunmei Hu, Fei Xu. LncRNA MIAT enhances cerebral ischaemia/reperfusion injury in rat model via interacting with EGLN2 and reduces its ubiquitin-mediated degradation. Journal of cellular and molecular medicine. 2021;25:(21):10140-10151
Chunmei Hu, Linhan Yang, Yi Wang, Shijie Zhou, Jing Luo, Yi Gu. Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop. Journal of ginseng research. 2021,45:(6):734-743
Yi Wang, Hongji Yang, Huirong Liu, Leo H. Buhler, Shaoping Deng. Strategies to halt 2019 novel coronavirus (SARS-CoV-2) spread for organ transplantation programs at the Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, China. American Journal of Transplantation. 2020;20(7): 1837-1839.
Yuping Liu, Lixia Qin, Rongsheng Tong, Ting Liu, Chen Ling, Tiantian Lei, Dingding Zhang, Yi Wang, Shaoping Deng. Regulatory changes in China on xenotransplantation and related products. Xenotransplantation.2020;27(3):e12601. (corresponding author)
Yong Yang, Hailian Wang, Kang Chen, Jun Zhou, Shaoping Deng, Yi Wang. Shelter hospital mode: how to prevent novel coronavirus infection 2019 (COVID-19) hospital-acquired infection? Infection Control & Hospital Epidemiology. 2020;41(7):872-873.(corresponding author)
Yuping Liu, Ting Liu, Tiantian Lei, Dingding Zhang, Suya Du, Lea Girani, Dandan Qi, Chen Lin, Rongsheng Tong and Yi Wang, RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy. International Journal of Molecular Medicine.2019;44(3):771-781. (corresponding author)
Wenjing He, Yaodong You, Suya Du, Tiantian Lei, Hailian Wang, Xiang Li, Xia He, Rongsheng Tong and Yi Wang, Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells via the regulation of YAP. Oncology Letters.2019;17(1):1008-1018. (corresponding author)
Yi Wang, Tiantian Lei, Liang Wei, Suya Du, Lea Girani and Shaoping Deng. Xenotransplantation in China: Present status. Xenotransplantation. 2019;26(1):e12490. (corresponding author)
Hanrui Zheng, Ting Liu, Tiantian Lei, Lea Girani, Yi Wang and Shaoping Deng. Promising Potentials of Tibetan Macaques in Xenotransplantation. Xenotransplantation. 2019;26(1):e12489.(corresponding author)
Lea Girani, Xiaofang Xie, Tiantian Lei, Liang Wei, Yi Wang and Shaoping Deng. Xenotransplantation in Asia. Xenotransplantation. 2019;26(1):e12493. (corresponding author)
Suya Du, Huirong Liu, Tiantian Lei, Xiaofang Xie，Hailian Wang, Xia He, Rongsheng Tong and Yi Wang, Mangiferin: An effective therapeutic agent against several disorders. Molecular Medicine Reports. 2018;18(6):4775-4786. (corresponding author)
Faguang Mu, Ting Liu, HanRui Zheng, Xiaofang Xie, Tiantian Lei, Xia He, Suya Du, Rongsheng Tong and Yi Wang, Mangiferin induces radiosensitization in glioblastoma cells by inhibiting nonhomologous end joining. Oncology Reports. 2018;40(6): 3663-3673. (corresponding author)
Hailian Wang, Xia He, Tiantian Lei, Yilong Liu, Guoli Huai, Minghan Sun and Shaoping Deng, Hongji Yang, Rongsheng Tong and Yi Wang, Mangiferin induces islet regeneration in aged mice through regulating p16INK4a. International Journal of Molecular Medicine.2018;41(6):3231-3242. (corresponding author)
Huirong Liu, Suya Du, Tiantian Lei, Hailian Wang, Xia He, Rongsheng Tong and Yi Wang. Multifaceted regulation and functions of YAP/TAZ in tumors (Review).Oncology Reports.2018;40(1): 16-28. (corresponding author)
Yong Yang, Tiantian Lei, Suya Du, Rongsheng Tong, Hailian Wang, Jiao Yang, Juan Huang, Minghan Sun, Zhi Dong and YiWang, Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma. International Journal of Oncology. 2018;52(3):709-720. (corresponding author)
Jie Peng, Hailian Wang, Xin Wang, Minghan Sun, Shaoping Deng and Yi Wang. YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells. International Journal of Molecular Medicine. 2017;41(1):164-172. (corresponding author)
Xin Wang, Guoli Huai, Hailian Wang, Yuande Liu, Ping Qi, Wei Shi, Jie Peng, Hongji Yang, Shaoping Deng and Yi Wang. Mutual regulation of the Hippo/Wnt/LPA/TGF-β signaling pathways and their roles in glaucoma. International Journal of Molecular Medicine. 2018;41(3):1201-1212. (corresponding author)
Xiang Li, Yi Wang, Shaoping Deng, Meeting report: The first international conference on xenotransplantation in Chengdu, China, Xenotransplantation, 2017; 24(6): 12376-12378.
Xia He, Suya Du, Tiantian Lei, Xiang Li, Yilong Liu, Hailian Wang, Rongsheng Tong and Yi Wang, PKM2 in carcinogenesis and oncotherapy, Oncotarget, 2017; 8(66): 110656-110670. (corresponding author)
Wenchun Jiang, Xin Li, Tongyu Li, Hailian Wang, Wei Shi, Ping Qi, Chunyang Li, Jie Chen, Jinku Bao, Guodong Huang and Yi Wang. Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer. International Journal of Oncology. 2017;50(3):823-834.(corresponding author)
Jianzhen Lv, Wen Xiong, Tiantian Lei, Hailian Wang, Minghan Sun, Erwei Hao, Zhiping Wang, Xiaoqi Huang, Shaoping Deng, Jiagang Deng and Yi Wang, Amygdalin ameliorates the progression of atherosclerosis in LDL receptor-deficient mice. Molecular Medicine Reports. 2017; 16(6): 8171-8179. (corresponding author)
Bingyu Zou, Hailian Wang, Yilong Liu, Ping Qi, Tiantian Lei, Minghan Sun and Yi Wang, Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3. Oncology Reports. 2017:38(3): 1431-1441. (corresponding author)
Guodong Huang, Bingyu Zou, Jianzhen Lv, Tongyu Li, Guoli Huai, Shaowei Xiang, Shilong Lu, Huan Luo, Yaping Zhang, Yi Jin and Yi Wang. Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway. International Journal of Molecular Medicine. 2017;39(3):559-568. (corresponding author)
Guodong Huang, Jianzhen Lv, Tongyu Li, Guoli Huai, Xiang Li, Shaowei Xiang, Longlong Wang, Zhenlin Qin, Jianli Pang, Bingyu Zou and Yi Wang. Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway. International Journal of Molecular Medicine. International Journal of Molecular Medicine. 2016;38(4):1179-1189. (corresponding author)
Guoli Huai, Ping Qi, Hongji Yang and Yi Wang. Characteristics of α-Gal epitope, anti-Gal antibody, α1,3 galactosyltransferse and its clinical exploitation. International Journal of Molecular Medicine. 2016, 37(1):11-20. (corresponding author)
Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang and Yi Wang. Molecular mechanisms underlying mangiferin-induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells. Molecular Medicine Reports. 2016; 13(4): 3423-3432. (corresponding author)
Chunyang Li, Jie Chen, Bangmin Lu, Zheng Shi, Hailian Wang, Bin Zhang, Kailiang Zhao, Wei Qi, Jinku Bao and Yi Wang. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS ONE. 2014; 9(7): e101526. (corresponding author)
Hailian Wang, Chunyang Li, Bin Zhang, Yuande Liu, Bangmin Lu, Zheng Shi, Na An, Liangkai Zhao, Jingjing Zhang, Jinku Bao and Yi Wang. Mangiferin facilitates islet regeneration and β-Cell proliferation through upregulation of cell cycle and β-Cell regeneration regulators. International Journal of Molecular Sciences. 2014; 15(5):9016-9035. (corresponding author)
Chunyang Li, Yi Wang, Hailian Wang, Zheng Shi, Na An, Yunde Liu，Jinku Bao, and Shaoping Deng. Molecular mechanisms of Lycoris aurea agglutinin-induced apoptosis and G2/M cell cycle arrest in human lung adenocarcinoma A549 cells, both in vitro and in vivo. Cell Proliferation. 2013; 46(3): 272-282.
Jianzhen Lv, Zijie Wang, Li Zhang, Hailian Wang, Yuande Liu, Chunyang Li, Jiagang Deng, Yi Wang and Jinku Bao. Mangiferin induces apoptosis and cell cycle arrest in MCF-7 cells both in vitro and in vivo. Journal of Animal and Veterinary Advances.2013,12(3):352-359. (corresponding author)
Yi Wang, Yuande Liu, Hailian Wang, Chunyang Li, Ping Qi and Jinku Bao. Agaricus bisporus lectins mediates islet β-cell proliferation through regulation of cell cycle proteins. Experimental Biology and Medicine.2012, 237(3): 287-289
Yi Wang, Hailian Wang, Yuande Liu, Chunyang Li, Ping Qi and Jinku Bao. Antihyperglycemic Effect of Gingsenoside Rh2 by Inducing Islet β-cell Regeneration in Mice. Hormone and Metabolic Research. 2012; 44(1):33-40.
Jiagang Deng, Chunyang Li, Hailian Wang, Erwei Hao, Zhengcai Du, Chuanhong Bao, Jianzhen Lv and Yi Wang. Anti-atherosclerotic effects mediated by the combination of probucol and amygdalin in apolipoprotein E-knockout mice fed with a high fat diet. Journal of Animal and Veterinary Advanes. 2012; 11(1): 20-25.(corresponding author)
Jiagang Deng, Chunyang Li, Hailian Wang, Erwei Hao, Jianzhen Lv and Yi Wang. Amygdalin mediates relieved atherosclerosis in apolipoprotein E deficient mice through the induction of regulatory T cells. Biochemical and Biophysical Research Communication. 2011, 411(3):523-529. (corresponding author)
Yi Wang, Leo Buhler, Shaoping Deng. Tibetan macaques, the ideal recipient for preclinical xenotransplantation study. Xenotransplantation.2019, 26(5):10-11.
Yi Wang, Jie Chen, Hongji Yang, Jianbo Zhang, Yi Gu, Shunyao Liao, Yan Mu, Man Lu, Hailian Wang, Shaoping Deng. Hormonal Manipulation Promotes the Regeneration of Pancreatic Islet Cells in Aged Mice. Diabetes. 2009, 58: A409-A410.
Rui He, Suya Du, Tiantian Lei, Xiaofang Xie, Yi Wang, Glycogen synthase kinase 3β in tumorigenesis and oncotherapy. Oncology Reports(corresponding author)
Xiaohong Zhang, Hailian Wang, Youwei Wang, Yu Lei, Kaiju Xu, Jie Zhang, Ying Han, Jun Zeng, Shaoping Deng, Yi Wang, Epidemiological and clinical based study on four passages of COVID-19 patients: Intervention at asymptomatic period contributes to early recovery. BMC Infectious Disease.
Jianzhen Lv, Wen Xiong, Tiantian Lei, Hailian Wang, Minghan Sun, Erwei Hao, Zhiping Wang, Xiaoqi Huang, Shaoping Deng, Jiagang Deng and Yi Wang, Amygdalin ameliorates the progression of atherosclerosis in LDL receptor-deficient mice, Molecular Medicine Reports, 2017, 16(6): 8171-8179.(corresponding author)
Wang Yi, Qi Ping, Du Guanghui. Study of Huangqi Guizhi decoction on the treatment of type 2 diabetic peripheral neuritis. Sichuan Journal of Physiological Sciences, 2016, 38(2):68-70. (Chinese)
Wang Yi, Qi Ping, Du Guanghui, Wang Hailian. Clinical effect study of musk pills for the treatment of angina pectoris of coronary heart disease Journal of Integrated Traditional Chinese and Western Medicine Cardiovascular Diseases. 2015,3(14):130-132. (Chinese)
Wang Yi, Chen Jie, Wang Hailian, Yang Hongji, Deng Shaoping. Effect of age on islet regeneration and apoptosis in mice with pancreatectomy. Chinese Journal of Diabetes. 2011. 3(1): 67-73. (Chinese)
Wang Yi, Chen Jie, Wang Hailian, Yang Hongji, Deng Shaoping. Study of mice islet regeneration model by partial pancreatectomy. Clinical Journal of Practical Hospital. 2010. 7(2):51-54. (Chinese)
Dengke Pan, Ting Liu, Tiantian Lei, Huibing Zhu, Yi Wang and Shaoping Deng. Progress in multiple genetically modified minipigs for xenotransplantation in China. Xenotransplantation, 2019;26(1): e12492.
Linlin Lai, Tingting Huang, Yi Wang, Yanfeng Liu, Jinghai Zhang and Yongbo Song. The expression of Analgesic-antitumor peptide (AGAP) from Chinese Buthus Martensii Karsch in Transgenic tobacco and tomato. Molecular Biology Reports, 2009, 36(5):1033-1039.
Huang Guodong, Huai Guoli, Yang Hongji, Wang Yi, Xiang Shaowei, Qin Zhenlin, Pang Jianli, Luo Huan, Zhang Yaping, Liu Zhenwei, Xu Jian, Lv Jianzhen. Study on the protective effect of compound Xiancao Granules on Human podocyte. Beijing Traditional Chinese Medicine. 2017,36(5):410-415. (Chinese)
Qi Ping, Wang Yi, Wen Xianxiu, Zhong Min. Clinical study on reducing neonatal ventilator associated pneumonia with quality nursing model. Sichuan Medicine, 2016, 37(3):355-357. (Chinese)
Qi Ping, Wang Yi, Wen Xianxiu, Du Guanghui. Study on the implementation and effect of continuous scheduling model in pediatric department. Journal of Clinical Nursing, 2015(6): 52-54. (Chinese)
Qi Ping, Wang Yi, Wen Xianxiu, Du Guanghui, Zhong Min. Study on the application of music intervention in infantile atomizing inhalation. Journal of Clinical Nursing, 2016, 15(4):77-79.
Qi Ping, Wang Yi, Du Guanghui, Wang Qingyan. Application of evidence-based nursing in preventing oral infections in children with leukemia. Clinical Journal of Practical Hospital,2015, 12(4), 131-133. (Chinese)
He Xia, Li Xiang, Yang Yong, Zhang Yuan, Yu Dongke, Wang Yi, Tong Rongsheng. Effect of multidrug resistance gene polymorphism on tacrolimus plasma concentration in Han population receiving renal transplant Chinese Clinical Pharmacology Magazine, 2015(9):718-721. (Chinese)
Qi Ping, Du Guanghui, Wang Yi, Xu Biying, Li Yu, Wang Qingyan. On the application of link quality control to pediatric IV infusion treatment. Sichuan Journal of Physiology. 2015, 37(1): 1283-1284. (Chinese)
Qi Ping, Wang Yi, Du Guanghui, Wang Qingyan. Application of evidence-based nursing in preventing oral infections in children with leukemia. Clinical Journal of Practical Hospital, 2015, 12(4), 131-133. (Chinese)
Du Guanghui, Zhao Guangbin, Lin Min, Wang Yi. Exploring new research and application method in building a two-way referral in the top three general hospitals and regional community health service center. Sichuan Medicine. 2012, (33) 11: 2053-2055. (Chinese)
Chen Yunfei, Wang Yi, Yang Hongji. Advance of liver xenotransplantation using pig organs. Chinese Tissue Engineering Research. 2012,16(5): 899-902. (Chinese)
Du Guanghui, Zhao Guangbin, Lin Min, Wang Yi. SWOT analysis of the general practice centre and tactics for its development. Sichuan Journal of Physiological Sciences, 2011, 33(4), 176-178. (Chinese)
Du Guanghui, Qi Ping, Wang Yi. Nursing and prevention experience on 120 cases of postpartum hemorrhage. Chinese Journal of Aesthetic Medicine, 2011, 20(s3):201-201. (chinese)
Chen Jie, Wang Yi, Zhang Jianbo, Wang Zhiying, Dong Wei. Evaluation of clinical application of serum specific IgG antibody on 14 foods intolerance. Journal of Practical Hospital Clinic. 2010, 7(1):67-69. (Chinese)
Du Guanghui, Yuan Suping, Qi Ping, Liu Huirong, Wang Yi. Discussion on the methods and effects of hierarchical professional training for outpatient guidance nurses. Journal of Clinical Rational Drug Use. 2010, 3(23): 29-30. (Chinese)
Song Yongbo, Sheng Yu, Wang Yi, Lai Linlin, Zhang Jinghai. Study on the expression of Anti-Neuroexcitation Peptide II (ANEPII) of Chinese Buthus Martensii Karsch in transgenic tobacco. Pharmaceutical Biotechnology. 2007. 14(2), 85-89. (Chinese)
Ⅵ.Fundings:
National Science Foundation of China, “the mechanism of ATM phosphorylation of PKM2 in homologous recombination repair of glioma DNA damage”, 2018-2021, Principal Investigator
Sichuan Science and Technology Bureau, Major International Cooperation Project, “Combining CRASPR/Cas genetically modified porcine islet xenotransplantation and CAR-Treg in the treatment of diabetes, 2022-2023, Principal Investigator
Sichuan Science and Technology Bureau, Major International Cooperation Project, “Combined application of genetic engineering and immune tolerance to study the effectiveness of islet xenotransplantation in the treatment of diabetes”, 2023-2024, co-Investigator
Sichuan Science and Technology Bureau, “Construction of a community-tertiary hospital integrated chronic obstructive pulmonary disease health management model based on the internet plus”, 2022-2023, co-Investigator
Chengdu Science and Technology Bureau, Key Research and Development Support Program, “iRGD-exosome vesicle encapsulated adriamycin in the treatment of glioma”, 2021-2022, Principal Investigator
Sichuan Medical Association, “GSK3β mediated DNA repair of breast cancer through the regulation of BRCA1 and result in the drug resistance”, 2020-2022, Principal Investigator
Sichuan Science and Technology Bureau, “Contrast-enhanced ultrasound in the study of mangiferin in the prevention of angiogenesis of ovarian cancer by regulating VEGF-Notch-DLL4 signaling pathway”, 2019-2021, co-Investigator
Sichuan Science and Technology Bureau, “An individualized new drug development and evaluation platform that integrates common key technologies of artificial intelligence and gene editing”, 2019-2021, co-Investigator
Sichuan Science and Technology Bureau, “Genetic effects of GWAS-linked loci in polycystic ovary syndrome”, 2018-2020, co-Investigator
Sichuan Science and Technology Bureau, “53BP1 regulates PKM2 to promote the repair of DNA damage in tumor cells”, 2018-2020, Principal Investigator
Chengdu Science and Technology Bureau's Key Research and Development Support Program, “GSK3β regulates BRCA1 and induces DNA damage HR repair in breast cancer”, 2018-2020, Principal Investigator
Personalized Drug Therapy State Key Laboratories Grant. “Amygdalin inhibits atherosclerosis by regulating TGF-β1/Smad signaling pathway”, completed, 2017-2020, Principal Investigator
Sichuan Provincial Health and Family Planning Commission, Key Research Program. “Mangiferin promotes islet regeneration in aged rats by regulating cell cycle factor and PDX-1 expression”, 2016-2019, Principal Investigator
Sichuan Province Human Resources and Social Sciences, Key Programs for Science and Technology, “Mangiferin-induced Insulin Regeneration in Aged Mice Promote Insulin Secretion”, 2015-2019, Principal Investigator
Sichuan Provincial Department of Science and Technology, Key Fundamental Research Funding, “The molecular mechanism of CDKL1 in endoplasmic reticulum stress-mediated breast cancer HCPT resistance”, 2015-2018, co-Investigator
National Natural Science Foundation of China, “Mechanism of the effect of melatonin receptor MTNR1B gene mutation on pregnancy glucose metabolism and insulin action”, 2015-2018, co-Investigator
Sichuan Provincial Department of Science and Technology, “Mangiferin promotes insulin secretion by regulating pancreatic islet regeneration in aged mice by regulating p16INK4a-D cyclins-cdk4-Rb signaling pathway and PDX-1 expression”, 2015-2017, Principal Investigator
The Open Funding of Information Technology Research Center, “The molecular mechanism of CDKL1 inhibitors based on virtual screening technology and its endoplasmic reticulum stress-mediated breast cancer resistance”, 2015-2017, co-Investigator
Start Funding of Sichuan Academy of Medical Science & Sichuan Provincial People’s Hospital, “Study on the islet regeneration induced by mangiferin in aged mice”, 2014-2017, Principal Investigator
National Science Foundation of China, “The role of pancreatic duct precursor cells in the regeneration of mouse islets induced by transcription factor PDX1”, 2010-2014, co-Investigator
National Science Foundation of China, “Anti-CD40/CD45RB monoclonal antibody and vascular bone marrow stem cell transplantation to induce immune tolerance mechanism in monkey kidney transplantation”, 2009-2013, co-Investigator
Danhong injection treatment of diabetic nephropathy, Buchang Pharmaceutical Company Funded Project, 2009-2012, co-Investigator
Sichuan Provincial Health and Family Planning Commission Research Project, “Islet regeneration in aged mice”, 2009-2011, co-Investigator
Sichuan Provincial Health and Family Planning Commission Research Project, “The regeneration of islets in the non-human primate, Tibet macque”, 2010-2012, co-Investigator
Sichuan Provincial Department of Science and Technology, “sertoli cells and islet cells co-transplantation induced xenograft immune tolerance”, 2008-2010, co-Investigator
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