Lulu Cai

Doctor of Engineering

With Certificate of Graduation for Doctorate Study

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CDDS Lab > Scientific Research > Paper Publications

Gambogic Acid, a Caged Xanthone: Therapeutic Effects, Pharmacokinetics, Toxicological Properties, and Delivery Platforms

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Affiliation of Author(s):[1] School of Pharmacy, Southwest Medical University, Luzhou 646000, China; Department of...
Journal:The American Journal of Chinese Medicine
Key Words:Gambogic Acid; Caged Xanthone; Therapeutic Actions; Pharmacokinetics; Toxicology; Delivery Platforms
Abstract:Many herbal and traditional medicines show promise… GA has demonstrated therapeutic potential against chronic inflammation, cancer, cardiovascular disorders… its mechanisms of action, pharmacokinetics, and toxicological profile remain unclear. Furthermore, no comprehensive review exists on nanotechnology-based delivery strategies for this compound. In this review, we summarize current knowledge of the molecular targets and signaling pathways of GA, systematically assess available pharmacokinetic data, safety considerations, and nanoplatform delivery systems, and highlight promising...
Volume:53
Issue:8
Page Number:2435–2464
ISSN No.:0192-415X​ / 1793-6853
Translation or Not:no