Lulu Cai
+
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Personal Information
Gender:Female
E-Mail:
Doctor of Engineering
With Certificate of Graduation for Doctorate Study
Gender:Female
E-Mail:3f576bce2f9b26ea560371e96fc27ce0ca4797c1cd74fe3d9d9fa48ab04aed191dcc2bdecaf1a8cde9fa1a59caa7ef194a303b906cd21df70b7d839ff1c9640a5f3dbd0e6761f2b020bdd6c46d471e80a9f2073860ca00fad2f4937d00e6d6fb24b7dee4e4dc9438e6bd1b669d93f82c4b6d9858020b214a72c83429440af8df
Affiliation of Author(s):[1]Department of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan...
Journal:International Journal of Nanomedicine
Key Words:lung cancer; curcumin; astragaloside IV; biomimetic liposomes; targeted delivery
Abstract:Background: Lung cancer is the malignant tumor with the highest incidence and lethality worldwide. Existing therapeutic modalities suffer from side effects, drug resistance, and limited efficacy… Curcumin (Cur) and astragaloside IV (AS) are promising natural anti-cancer agents; however, poor aqueous solubility and low bioavailability limit clinical efficacy. Methods/Results: Optimal synergistic ratio determined; CM@AC liposomes 111.86±4.12 nm, ζ≈−20.8 mV, EE Cur 63.81%, AS 60.38%; superior tumor targeting, immune evasion, enhanced cytotoxicity/apoptosis/invasion inhibition; in vivo tumor ...
Volume:21
Page Number:558285
ISSN No.:1176-9114
Translation or Not:no
Address: Shahe Campus:No.4, Section 2, North Jianshe Road, 610054 | Qingshuihe Campus:No.2006, Xiyuan Ave, West Hi-Tech Zone, 611731 | Chengdu, Sichuan, P.R.China © 2010 University of Electronic Science and Technology of China. All Rights Reserved
Click: | The Last Update Time:.. | University of Electronic Science and Technology of China