个人简介
段旭君，电子科技大学生命科学与技术学院教授，博士生导师。国家自然科学基金优青（2023）;国际脑图谱年会（OHBM）Keynote Speaker（2023）；中国图象图形学学会石青云女科学家奖（2024）; 科技部重点研发计划青年科学家项目负责人（2024）；四川省杰出青年基金（2024）。中国认知科学学会 儿童脑智发展与健康专业委员会 副主任委员;中国遗传学会 行为遗传分会 委员;中国神经科学学会 儿童认知与脑功能障碍分会 委员;中国自动化学会 智能健康与生物信息专委会 委员;中国图象图形学学会 视觉认知与计算专委会 委员;四川省神经科学学会 理事；国际脑影像期刊《Imaging Neuroscience》编委。
主要研究领域为孤独症脑影像，在孤独症脑动态网络成像、多模态融合成像、脑成像引导的神经调控等方面开展了一系列研究，建立了“评估-干预-成像”的孤独症智能诊疗平台，并开展临床应用，发起并成立中国孤独症脑影像联盟。相关研究成果以第一/通讯作者发表在PNAS, Biological Psychiatry，Science Bulletin，eLife等期刊；主持5项国家自然科学基金项目和1项科技部重点研发计划青年科学家项目（均为孤独症脑影像领域）。
主持或参与的科研项目
国家重点研发计划青年科学家项目，2024YFF0509100，孤独症仿生光声刺激的神经反馈与调控研究，2024/12-2029/11，400万元，在研，主持
国家自然科学基金优秀青年基金，82322035，孤独症脑成像，2024/01-2027/12, 200万元，主持
广东省重点领域研发计划， 孤独症早期诊断及干预技术研究，2023B0303020001，2023/01-2025/12，500万元，在研，主持
国家自然科学基金面上项目，62273076，多源融合的孤独症神经机制建模与辅助诊疗算法研究，2023/01-2026/12，53万元，在研，主持
国家自然科学基金面上项目，81871432，经颅磁刺激干预儿童孤独症的多模态影像学神经机制研究，2019/01-2022/12, 56万元，已结题，主持
国家自然科学基金面上项目，61673089，儿童孤独症早期干预的脑可塑性多模态磁共振研究，2017/01-2020/12, 62万元，已结题，主持
获奖
1. 中国图象图形学学会石青云女科学家奖，段旭君，2024年，排名（1/1）
2. 磁共振脑网络成像新方法及其对癫痫脑机制的研究，四川省科学技术进步奖，自然科学类一等奖，2018，排名（5/5）
3. 癫痫多模态磁共振成像新技术临床应用研究，中华人民共和国教育部，科技进步一等奖 2013年，排名（17/18）
专利
1. 段旭君，李镭，肖金明，陈华富，基于磁共振成像的个体空间经颅磁刺激精准定位导航的方法。专利号：ZL 2022 1 0373878.4
2. 陈彦弛，段旭君，廖伟，刘宏宇，雷鑫峰，王润诗。一种基于杏仁核功能环路介导的重复经颅磁刺激影像导航的方法。2018，申请号：201810125830.5
3. 廖伟，段旭君，陈华富。一种基于fMRI探测动态脑自发活动的数据方法。专利号：ZL 2016 1 0524807.4
软件著作权
1. 段旭君，单晓龙，肖金明，何长春，陈华富。孤独症眼动评估软件。登记号：2020SR0295320。
2. 龙治良，段旭君，廖伟，陈华富。基于神经影像亚分类软件。登记号：2020SR0347621。
3. 陈华富，陈恒，何长春，郭肖楠，卢凤梅，段旭君。双聚类大脑皮下脑区亚区定位软件。登记号：2019SR0772808。
4. 段旭君，李镭，陈华富，功能环路介导的深部脑刺激定位软件。登记号：2023SR0280008.
代表性论文：
2025年
1. 王笑天，等，孤独症儿童大脑灰质体积异常的性别差异性影像遗传学分析。中华医学杂志。2025
2. Xiaolong Shan, Ya Li, Jinming Xiao, Xiaotian Wang, Xinyue Huang, Lei Li, Yu Feng, Weixin Zhao, Huafu Chen*, Xujun Duan*. Developmental Shift from Intrinsic Hyper- to Hypo- Connectivity Occurring at Pre- Adolescence in Autism Spectrum Disorder. Autism Research, 2025, 18(11):2254-2264.
3. Yu Feng, Weixing Zhao, Youyi Li, Qin Yin, Xiaotian Wang, Xinyue Huang, Lei Li, Xiaolong Shan, Wanrou Hu, Yating Ming, Peng Wang, Jinming Xiao*, Huafu Chen*, Xujun Duan*. Diffusion trajectory of atypical morphological development in autism. Communications biology, 2025, 8:1476. 2025 Oct 16
4. 段旭君. 早发性精神分裂症和孤独症脑指纹: 相似而不同，科学通报。Xujun Duan. Brain fingerprints of early-onset schizophrenia and autism: similar but different (in Chinese). Chin Sci Bull, doi: 10.1360/TB-2024-0717.
5. Jinming Xiao, Qing Yin, Lei Li, Yao Meng, Xiaobo Liu, Wanrou Hu, Xinyue Huang, Yu Feng, Xiaolong Shan, Weixing Zhao, Peng Wang, Xiaotian Wang, Youyi Li, Huafu Chen*, Xujun Duan*. Tracking causal pathways in TMS-evoked brain responses. PLoS Computational Biology, Aceepted. 2025 Jul 28; 21(7):e1013316
6. Xinyue Huang, Weixing Zhao, Rui Feng, Yuanyue Zhou, Jia Wang, Jinming Xiao, Lei Li, Xiaolong Shan, Yu Feng, Yating Ming, Jing Cao, Xiaodong Kang, Lijie Wu, Huafu Chen*, Xujun Duan*. Linking gut microbiome profiles and white matter integrity to social behavior in young autistic children: from the perspective of individual variation. Science Bulletin, 2025, 70(12):1927-1931.
7. Jinming Xiao#, Yating Ming#, Lei Li#, Xinyue Huang, Yuanyue Zhou, Jianjun Ou, Juan Kou, Rui Feng, Rui Ma, Qingyu Zheng, Xiaolong Shan, Yao Meng, Wei Liao, Yingli Zhang, Ting Wang, Yangying Kuang, Jing Cao, Shijun Li, Hua Lai, Jia Chen, Qi Wang, Xiaoli Dong, Xiaodong Kang, Huafu Chen*, Vinod Menon*, Xujun Duan*. Personalized theta-burst stimulation enhances social skills in young minimally verbal children with autism: a double-blind randomized controlled trial. Biological Psychiatry, 2025, 97(12):1139-1149.
8. Xujun Duan*, Xiaolong Shan, Lucina Q. Uddin, Huafu Chen*. The future of disentangling the heterogeneity of autism with neuroimaging studies. Biological Psychiatry, 2025, 97(5):428-438.
9. Lei Li, Jinming Xiao, Weixing Zhao, Qingyu Zheng, Xinyue Huang, Xiaolong Shan, Yating Ming, Peng Wang, Zhen Wu, Huafu Chen*, Vinod Menon*, Xujun Duan*. Mother-child dyadic interactions shape children’s social brain and theory of mind. eLife, 2025, https://doi.org/10.7554/eLife.103017.1
10. Lei Li, Xinyue Huang, Qingyu Zheng, Jinming Xiao, Xiaolong Shan, Huafu Chen*, Xujun Duan*. Similarity or complementarity? Understanding marital relationships in terms of sexual dimorphism in brain morphometry and gender roles. NeuroImage, 2025, 305:120974.
11. Lei Li, Xinyue Huang, Qingyu Zheng, Jinming Xiao, Xiaolong Shan, Huafu Chen*, Xujun Duan*. Similar trajectories of psychological states predict marital satisfaction. Imaging Neuroscience, 2025, 3:imag_a_00466.
12. Xiaolong Shan, Peng Wang, Qing Yin, Youyi Li, Xiaotian Wang, Yu Feng, Jinming Xiao, Lei Li, Xinyue Huang, Huafu Chen*, Xujun Duan*. Atypical dynamic neural configuration in autism spectrum disorder and its relationship to gene expression profiles, European Child & Adolescent Psychiatry, 2025, 34:169-179.
2024年
13. Weihua Zhao*, Keith M. Kendrick, Xujun Duan*. Challenges and prospects in the autism spectrum disorder field. Medicine Plus, 2024, 1:100045.
14. Yu Feng, Xinyue Huang, Weixin Zhao, Yating Ming , Yuanyue Zhou, Rui Feng, Jinming Xiao, Xiaolong Shan, Xiaodong Kang, Xujun Duan*, Huafu Chen*. Association among internalizing problems, white matter integrity, and social difficulties in children with autism spectrum disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2024, 135:111109.
15. Xinyue Huang, Leying Gao, Jiming Xiao, Lei Li, Xiaolong Shan, Huafu Chen, Xiaoqian Chai*, Xujun Duan*. Family environment modulates linkage of transdiagnostic psychiatric phenotypes and dissociable brain features in the developing brain, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2024, 9(9):928-938.
16. 单晓龙，陈华富，段旭君*，孤独症谱系障碍多模态磁共振脑影像模式识别, 心理科学进展, 2024, 32(7):548-564.
17. Weixing Zhao, Lei Li, Xiujie Yang, Xiaotian Wang, Juan Kou, Jia Chen, Huafu Chen, Qi Wang*, Xujun Duan*. Brain development of a school-aged boy with autism spectrum condition talented in arithmetic: a case report. Psychoradiology, 2024, 4:kkae008.
18. Xiaolong Shan, Lucina Q. Uddin, Rui Ma, Pengfei Xu, Jinming Xiao, Lei Li, Xinyue Huang, Yu Feng, Changchun He, Huafu Chen*, Xujun Duan*. Disentangling the individual-shared and individual-specific subspace of altered brain functional connectivity in autism spectrum disorder, Biological Psychiatry, 2024, 95(9):870-880.
2023年
19. Xinyue Huang, Yating Ming, Weixing Zhao, Rui Feng, Yuanyue Zhou, Lijie Wu, Jia Wang, Jinming Xiao, Lei Li, Xiaolong Shan, Jing Cao, Xiaodong Kang, Huafu Chen*, Xujun Duan*. Developmental prediction modeling based on diffusion tensor imaging uncovering age-dependent heterogeneity in early childhood autistic brain, Molecular Autism, 2023, 14:41.
20. 郑清予，李镭，肖金明，陈华富，段旭君*. 孤独症谱系障碍默认网络与任务正激活网络交互的共激活模式研究, 中华精神科杂志, 2023, 56 (4):284-291.
2022 年
21. Xujun Duan*, Huafu Chen. Mapping brain functional and structural abnormities in autism spectrum disorder: moving towards precision treatment. Psychoradiology, 2022, 2:78-85.
22. Jinming Xiao, Lucina Q. Uddin, Yao Meng, Lei Li, Leying Gao, Xiaolong Shan, Xinyue Huang, Wei Liao, Huafu Chen*, Xujun Duan*. A spatio-temporal decomposition framework for dynamic functional connectivity in the human brain. NeuroImage, 2022, 263:119618.
23. Lei Li, Xinyue Huang, Jinming Xiao, Qingyu Zheng, Xiaolong Shan, Changchun He, Wei Liao, Huafu Chen*, Vinod Menon*, Xujun Duan*. Neural synchronization predicts marital satisfaction. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(34):e2202515119.
24. Lei Li#, Xiaoran Su#, Qingyu Zheng, Jinming Xiao, XinYue Huang, Wan Chen, Kaihua Yang, Lei Nie, Xin Yang, Huafu Chen*, Shengli Shi*, Xujun Duan*. Cofluctuation analysis reveals aberrant default mode network patterns in adolescents and youths with autism spectrum disorder. Human Brain Mapping, 2022, 43(15):4722-4732.
25. Xiaolong Shan, Lucina Q. Uddin, Jinming Xiao, Changchun He, Zihan Ling, Lei Li, Xinyue Huang, Huafu Chen, Xujun Duan*. Mapping the heterogeneous brain structural phenotype of autsim spectrum disorder using the normative model. Biological Psychiatry, 2022, 91:967-976.
26. Xiaofen Zong, Jiangbo Zhang, Lei Li, Tao Yao, Simeng Ma, Lijun Kang, Nan Zhang, Zhaowen Nie, Zhongchun Liu*, Junjie Zheng, Xujun Duan*, Maolin Hu*. Virtual histology of morphometric similarity network after risperidone monotherapy and imaging-epigenetic biomarkers for treatment response in first-episode schizophrenia. Asian Journal of Psychiatry, 2023, 80:103406.
2021年
27. Xinyue Huang, Lei Li, Zihan Ling, Leying Gao, Huafu Chen, Xujun Duan*. Gut microbiome diversity mediates the association between right dorsolateral prefrontal cortex and anxiety level. Brain Image and Behavior, 2022, 16(1):397-405.
28. Heng Chen#, Fengmei Lu#, Xiaonan Guo, Yajing Pang, Changchun He, Shaoqiang Han, Xujun Duan*, Huafu Chen*. Dimensional Analysis of Atypical Functional Connectivity of Major Depression Disorder and Bipolar Disorder. Cerebral Cortex, 2022, 32(6):1307-1317.
29. Changchun He, Jesus M. Cortes, Xiaodong Kang, Jing Cao, Heng Chen, Xiaonan Guo, Ruishi Wang, Lingyin Kong, Xinyue Huang, Jinming Xiao, Xiaolong shan, Rui Feng, Huafu Chen, Xujun Duan*. Individual-based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorder. Human Brain Mapping, 2021, 42(10):3282-3294.
30. Jinming Xiao, Huafu Chen*, Xiaolong Shan, Changchun He, Ya Li, Xiaonan Guo, Heng Chen, Wei Liao, Lucina Q. Uddin*, Xujun Duan*. Linked social–communication dimensions and connectivity in functional brain networks in autism spectrum disorder. Cerebral Cortex, 2021, 31(8):3899-3910.
31. Xiaonan Guo, Xujun Duan*, John Suckling, JiaWang, Xiaodong Kang, Heng Chen, Bharat B. Biswal, Jing Cao, Changchun He, Jinming Xiao, Xinyue Huang, Runshi Wang, Shaoqiang Han, Yun-Shuang Fan, Jing Guo, Jingping Zhao, Lijie Wu* and Huafu Chen*. Mapping progressive gray matter alterations in early childhood autistic brain. Cerebral Cortex, 2021, 31(3):1500-1510.
32. Xujun Duan#, Changchun He#, Jianjun Ou, Runshi Wang, Jinming Xiao, Lei Li, Renrong Wu, Yan Zhang*, Jingping Zhao*, Huafu Chen*. Reduced hippocampal volume and its relationship with verbal memory and negative symptoms in treatment-naive first-episode adolescent-onset schizophrenia. Schizophrenia Bulletin, 2021, 47(1):64-74.
教育经历
电子科技大学 工学学士学位
电子科技大学 工学博士学位
工作经历
2021.1-至今
电子科技大学生命科学与技术学院
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研究员
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研究员
2014.7-至今
电子科技大学生命科学与技术学院
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副教授
2013.7-2014.6
电子科技大学生命科学与技术学院
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讲师